Search results for "Sequence Analysis"

showing 10 items of 1349 documents

The Greenland shark Somniosus microcephalus—Hemoglobins and ligand-binding properties

2017

A large amount of data is currently available on the adaptive mechanisms of polar bony fish hemoglobins, but structural information on those of cartilaginous species is scarce. This study presents the first characterisation of the hemoglobin system of one of the longest-living vertebrate species (392 +/- 120 years), the Arctic shark Somniosus microcephalus. Three major hemoglobins are found in its red blood cells and are made of two copies of the same a globin combined with two copies of three very similar beta subunits. The three hemoglobins show very similar oxygenation and carbonylation properties, which are unaffected by urea, a very important compound in marine elasmobranch physiology.…

---0301 basic medicinegenetic structuresProtein ConformationGreenlandlcsh:MedicineRESONANCE RAMAN-SPECTRAHETERODONTUS-PORTUSJACKSONISpectrum Analysis RamanBiochemistrychemistry.chemical_compoundHemoglobinsProtein structureAMINO-ACID SEQUENCEAnimal CellsSequence Analysis ProteinRed Blood CellsUreaNOTOTHENIOID FISHESPost-Translational Modificationlcsh:ScienceHemeChondrichthyesMultidisciplinarybiologyChemistryOrganic CompoundsChemical ReactionsVertebrateEukaryotaMOLECULAR ADAPTATIONSMicrocephalusGlobinsChemistryBiochemistryOptical EquipmentVertebratesPhysical SciencesEngineering and TechnologyCellular TypesResearch ArticleEnvironmental MonitoringProtein BindingQUATERNARY STRUCTURESAllosteric regulationEquipmentSTRETCHING FREQUENCIESHeme03 medical and health sciencesOXYGEN-BINDINGbiology.animalAnimals14. Life underwaterGlobinHemoglobinPhotolysisBlood Cells030102 biochemistry & molecular biologyLaserslcsh:ROrganic ChemistryOrganismsChemical CompoundsBiology and Life SciencesProteinsxxxCell Biologybiology.organism_classificationCARTILAGINOUS FISHOxygen030104 developmental biologySomniosusFishSharkslcsh:QHemoglobinProtein MultimerizationELASMOBRANCH HEMOGLOBINElasmobranchiiPLoS ONE
researchProduct

Recombinant laccase from Pediococcus acidilactici CECT 5930 with ability to degrade tyramine

2017

Biogenic amines degradation by bacterial laccases is little known, so we have cloned and heterologously expressed, in E. coli, a new laccase from Pediococcus acidilactici CECT 5930 (Lpa5930), a lactic acid bacterium commonly found in foods able to degrade tyramine. The recombinant enzyme has been characterized by physical and biochemical assays. Here we report the optimization of expression and purification procedures of this laccase. DNA encoding sequence of laccase from P. acidilactici was amplified by PCR and cloned into the expression plasmid pET28a for induction by isopropyl-β-D-thiogalactoipyranoside. Protein expression was performed in E. coli BL21(DE3) harboring pGro7 plasmid expres…

0106 biological sciences0301 basic medicineArabinoseMolecular biologylcsh:MedicineLaccasesBiochemistryBiotecnologia01 natural sciencesSubstrate Specificitylaw.inventionDatabase and Informatics Methodschemistry.chemical_compoundlawRecombinant Protein PurificationCloning MolecularAmineslcsh:Sciencechemistry.chemical_classificationMultidisciplinaryABTSbiologyOrganic CompoundsTemperatureHydrogen-Ion ConcentrationTyramineRecombinant ProteinsEnzymesChemistryRecombination-Based AssayBiochemistryPhysical SciencesRecombinant DNAElectrophoresis Polyacrylamide GelOxidation-ReductionSequence AnalysisResearch ArticleProtein PurificationBioinformaticsTyramineLibrary ScreeningDNA constructionResearch and Analysis Methods03 medical and health sciencesBacterial ProteinsSequence Motif Analysis010608 biotechnologyAmino Acid SequenceBenzothiazolesPediococcus acidilacticiLaccaseMolecular Biology Assays and Analysis TechniquesBase SequenceMolecular massLaccaseOrganic Chemistrylcsh:RChemical CompoundsBiology and Life SciencesProteinsPediococcus acidilacticiSequence Analysis DNAbiology.organism_classificationMolecular biology techniques030104 developmental biologyEnzymechemistryPlasmid ConstructionEnzymologySpectrophotometry Ultravioletlcsh:QSulfonic AcidsEnzimsProteïnesPurification TechniquesPLOS ONE
researchProduct

A Metabarcoding Survey on the Fungal Microbiota Associated to the Olive Fruit Fly.

2017

The occurrence of interaction between insects and fungi is interesting from an ecological point of view, particularly when these interactions involve insect pests and plant pathogens within an agroecosystem. In this study, we aimed to perform an accurate analysis on the fungal microbiota associated to Bactrocera oleae (Rossi) through a metabarcoding approach based on 454 pyrosequencing. From this analysis, we retrieved 43,549 reads that clustered into 128 operational taxonomic units (OTUs), of which 29 resulted in the “core” associate fungi of B. oleae. This fungal community was mainly represented by sooty mould fungi, such as Cladosporium spp., Alternaria spp. and Aureobasidium spp., by pl…

0106 biological sciences0301 basic medicineBactrocera oleaeOlive fruit flySoil ScienceAureobasidium01 natural sciences03 medical and health sciencesMicrobial ecologyPseudocercospora454 PyrosequencingAscomycotaOleaBotanyColletotrichumAnimalsDNA Barcoding TaxonomicPseudocercosporaEcology Evolution Behavior and SystematicsEcological nicheHigh-throughput sequencingEcologybiologyBase SequenceEcologyfungiTephritidaefood and beveragesSettore AGR/12 - Patologia VegetaleAlternariaHigh-Throughput Nucleotide SequencingSequence Analysis DNAbiology.organism_classificationAlternaria030104 developmental biologySettore AGR/11 - Entomologia Generale E ApplicataColletotrichumDNA Intergenic454 Pyrosequencing; Bactrocera oleae; Cladosporium; Colletotrichum; High-throughput sequencing; PseudocercosporaCladosporium010606 plant biology & botanyCladosporiumMycobiomeMicrobial ecology
researchProduct

An SNP-based saturated genetic map and QTL analysis of fruit-related traits in Zucchini using Genotyping-by-sequencing

2016

[EN] Background: Cucurbita pepo is a cucurbit with growing economic importance worldwide. Zucchini morphotype is the most important within this highly variable species. Recently, transcriptome and Simple Sequence Repeat (SSR)- and Single Nucleotide Polymorphism (SNP)-based medium density maps have been reported, however further genomic tools are needed for efficient molecular breeding in the species. Our objective is to combine currently available complete transcriptomes and the Zucchini genome sequence with high throughput genotyping methods, mapping population development and extensive phenotyping to facilitate the advance of genomic research in this species. Results: We report the Genoty…

0106 biological sciences0301 basic medicineCartographyCandidate geneGenotyping TechniquesPopulationQuantitative Trait LociGenomicsSingle-nucleotide polymorphismFlowersBiologyQuantitative trait locusGBS01 natural sciencesPolymorphism Single NucleotideCandidate genes03 medical and health sciencesCucurbitaGeneticsGens MapatgeeducationGenotyping TechniquesGeneticsMolecular breedingWhole genome sequencingeducation.field_of_studyPigmentationChromosome MappingRILfood and beveragesGenomicsCucurbita pepoGENETICAGenòmica030104 developmental biologyPhenotypePhenotypingFruitSequence Analysis010606 plant biology & botanyBiotechnologyResearch Article
researchProduct

Chloroplast genomes of Rubiaceae: Comparative genomics and molecular phylogeny in subfamily Ixoroideae.

2020

In Rubiaceae phylogenetics, the number of markers often proved a limitation with authors failing to provide well-supported trees at tribal and generic levels. A robust phylogeny is a prerequisite to study the evolutionary patterns of traits at different taxonomic levels. Advances in next-generation sequencing technologies have revolutionized biology by providing, at reduced cost, huge amounts of data for an increased number of species. Due to their highly conserved structure, generally recombination-free, and mostly uniparental inheritance, chloroplast DNA sequences have long been used as choice markers for plant phylogeny reconstruction. The main objectives of this study are: 1) to gain in…

0106 biological sciences0301 basic medicineChloroplastsPlant GenomesCoffeaRubiaceaePlant SciencePlant Genetics01 natural sciencesGenomePlant GenomicsPlastidsGenome EvolutionPhylogenyData ManagementMultidisciplinaryIxoroideaeQDNA ChloroplastRHigh-Throughput Nucleotide Sequencingfood and beveragesPhylogenetic AnalysisGenomicsPhylogeneticsChloroplast DNAEngineering and TechnologyMedicineGenome PlantResearch ArticleBiotechnologyGenome evolutionComputer and Information SciencesNuclear genePlant Cell BiologyScienceGenomicsBioengineeringBiology010603 evolutionary biologyPolymorphism Single NucleotideMolecular EvolutionEvolution Molecular03 medical and health sciencesChloroplast GenomeGeneticsEvolutionary SystematicsGenome ChloroplastTaxonomyComparative genomicsEvolutionary BiologyBiology and Life SciencesComputational BiologyCell BiologySequence Analysis DNAComparative Genomicsbiology.organism_classificationGenome AnalysisGenomic Libraries030104 developmental biologyEvolutionary biologyPlant BiotechnologyReference genomePLoS ONE
researchProduct

Evaluation of chloroplast genome annotation tools and application to analysis of the evolution of coffee species.

2018

International audience; Chloroplast sequences are widely used for phylogenetic analysis due to their high degree of conservation in plants. Whole chloroplast genomes can now be readily obtained for plant species using new sequencing methods, giving invaluable data for plant evolution However new annotation methods are required for the efficient analysis of this data to deliver high quality phylogenetic analyses. In this study, the two main tools for chloroplast genome annotation were compared. More consistent detection and annotation of genes were produced with GeSeq when compared to the currently used Dogma. This suggests that the annotation of most of the previously annotated chloroplast …

0106 biological sciences0301 basic medicineChloroplastsPlant GenomesPlant SciencePlant Genetics01 natural sciencesGenomeCoffeeDatabase and Informatics MethodsPlant GenomicsPlastidsPhylogenyData Management2. Zero hungerPlant evolutionMultidisciplinarybiologyPhylogenetic treeQRfood and beveragesPhylogenetic AnalysisGenome projectGenomicsPhylogenetics[INFO.INFO-MA]Computer Science [cs]/Multiagent Systems [cs.MA]MedicineEngineering and Technology[INFO.INFO-DC]Computer Science [cs]/Distributed Parallel and Cluster Computing [cs.DC]Cellular Structures and OrganellesCellular TypesSequence AnalysisResearch ArticleBiotechnologyComputer and Information SciencesBioinformaticsSciencePlant Cell BiologyBioengineering[INFO.INFO-SE]Computer Science [cs]/Software Engineering [cs.SE]Coffea canephoraGenes PlantResearch and Analysis Methods010603 evolutionary biology[INFO.INFO-IU]Computer Science [cs]/Ubiquitous ComputingEvolution Molecular[INFO.INFO-CR]Computer Science [cs]/Cryptography and Security [cs.CR]03 medical and health sciencesPhylogeneticsChloroplast GenomePlant CellsGeneticsEvolutionary SystematicsGenome ChloroplastTaxonomyEvolutionary BiologyCoffea arabicaCoffeafungiBiology and Life SciencesComputational BiologyMolecular Sequence AnnotationSequence Analysis DNACell Biology15. Life on landbiology.organism_classificationGenome Analysis[INFO.INFO-MO]Computer Science [cs]/Modeling and SimulationGenome Annotation030104 developmental biologyEvolutionary biology[INFO.INFO-ET]Computer Science [cs]/Emerging Technologies [cs.ET]Plant BiotechnologySequence AlignmentPloS one
researchProduct

Gibberellin reactivates and maintains ovary-wall cell division causing fruit set in parthenocarpic Citrus species

2016

[EN] Citrus is a wide genus in which most of the cultivated species and cultivars are natural parthenocarpic mutants or hybrids (i.e. orange, mandarin, tangerine, grapefruit). The autonomous increase in GA(1) ovary concentration during anthesis was suggested as being the stimulus responsible for parthenocarpy in Citrus regardless of the species. To determine the exact GA-role in parthenocarpic fruit set, the following hypothesis was tested: GA triggers and maintains cell division in ovary walls causing fruit set. Obligate and facultative parthenocarpic Citrus species were used as a model system because obligate parthenocarpic Citrus sp (i.e. Citrus unshiu) have higher GA levels and better n…

0106 biological sciences0301 basic medicineCitrusCell divisionFruit setCitruFlowersPlant ScienceOrange (colour)BiologyParthenocarpy01 natural sciencesPaclobutrazol03 medical and health scienceschemistry.chemical_compoundPlant Growth RegulatorsGeneticAnthesisCell WallGene Expression Regulation PlantBotanyPRODUCCION VEGETALGeneticsGibberellinPhylogenyFruit treePlant Growth Regulatorfood and beveragesSequence Analysis DNAGeneral Medicinebiology.organism_classificationGibberellinsUp-RegulationCitrus unshiu030104 developmental biologychemistryFlowerFruitMicroscopy Electron ScanningParthenocarpyGibberellinAgronomy and Crop ScienceCell DivisionFruit tree010606 plant biology & botanyPlant Science
researchProduct

Spatio-temporal dynamics of genetic variation in the Iberian lynx along its path to extinction reconstructed with ancient DNA

2017

here is the tendency to assume that endangered species have been both genetically and demographically healthier in the past, so that any genetic erosion observed today was caused by their recent decline. The Iberian lynx (Lynx pardinus) suffered a dramatic and continuous decline during the 20th century, and now shows extremely low genome- and species-wide genetic diversity among other signs of genomic erosion. We analyze ancient (N = 10), historical (N = 245), and contemporary (N = 172) samples with microsatellite and mitogenome data to reconstruct the species' demography and investigate patterns of genetic variation across space and time. Iberian lynx populations transitioned from low but …

0106 biological sciences0301 basic medicineConservation of Natural ResourcesMetapopulationBiologyLincesExtinction Biological010603 evolutionary biology01 natural sciencesEndangered speciesgenetic erosion03 medical and health sciencesGenetic driftGenetic variationGeneticsAnimalsDNA AncientGenetic erosionancient DNAMolecular BiologyQH426Institut für Biochemie und BiologieDiscoveriesEcology Evolution Behavior and SystematicsPaleobiologíaGenetic diversityQLGenomeExtinctionAncient DNAEcologyQHEndangered SpeciesGenetic DriftGenetic VariationPaleogeneticsParque nacional de DoñanaSequence Analysis DNAIberian lynxGenéticahumanities030104 developmental biologyAncient DNAGenome MitochondrialLynxPaleogeneticsGenetic erosionpaleogeneticsMicrosatellite Repeats
researchProduct

Frequent colonization and little in situ speciation in Senecio in the tropical alpine-like islands of eastern Africa.

2016

Premise of the study Floras of continental habitat islands, like those of islands, originate mostly through colonization, which can be followed by in situ speciation. We here address the question of the relative importance of colonization and in situ diversification in the high-altitude areas of the eastern African high mountains, the tropical Afroalpine Region, using the most species-rich genus in the region, Senecio, as an example. Methods We expanded earlier Senecioneae phylogenies by adding more tropical African species and analyzed our phylogenetic tree biogeographically. Key results Senecio contains at least five clades with tropical African species, all of them containing tropical af…

0106 biological sciences0301 basic medicineDNA PlantInsular biogeographyGenetic SpeciationPlant ScienceSenecio010603 evolutionary biology01 natural sciences03 medical and health sciencesGenusGeneticsColonizationSenecioEcology Evolution Behavior and SystematicsPhylogenybiologyEcologySenecioneaeSequence Analysis DNAAfrica Easternbiology.organism_classificationPhylogeography030104 developmental biologyTaxonHabitatGlobal biodiversityAmerican journal of botany
researchProduct

Gene expression in diapausing rotifer eggs in response to divergent environmental predictability regimes

2020

AbstractIn unpredictable environments in which reliable cues for predicting environmental variation are lacking, a diversifying bet-hedging strategy for diapause exit is expected to evolve, whereby only a portion of diapausing forms will resume development at the first occurrence of suitable conditions. This study focused on diapause termination in the rotifer Brachionus plicatilis s.s., addressing the transcriptional profile of diapausing eggs from environments differing in the level of predictability and the relationship of such profiles with hatching patterns. RNA-Seq analyses revealed significant differences in gene expression between diapausing eggs produced in the laboratory under com…

0106 biological sciences0301 basic medicineEvolutionScienceRotiferaZoologyRotiferBiologyDiapauseRotífers01 natural sciencesArticleGenètica molecularTranscriptome03 medical and health sciencesGene expressionAnimalsPredictabilityMultidisciplinaryEcologySequence Analysis RNAHatchingReproduction010604 marine biology & hydrobiologyQREmbryoBrachionusbiology.organism_classificationDiapauseComputational biology and bioinformaticsEcologia030104 developmental biologyMedicine
researchProduct